FGD5 antibody (AA 269-539)

Catalog No. ABIN7153265

Product Details anti-FGD5 Antibody

Target: FGD5 (FYVE, RhoGEF and PH Domain Containing 5 (FGD5))

Binding Specificity: AA 269-539

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGD5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human FYVE, RhoGEF and PH domain-containing protein 5 protein (269-539AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FGD5

Target: FGD5 (FYVE, RhoGEF and PH Domain Containing 5 (FGD5))

Alternative Name: FGD5 (FGD5 Products)

Synonyms: ZFYVE23 antibody, C330025N11Rik antibody, mFLJ00274 antibody, FYVE, RhoGEF and PH domain containing 5 antibody, Fgd5 antibody, FGD5 antibody

Background:

Background: Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.

Aliases: FGD5 antibody, ZFYVE23FYVE antibody, RhoGEF and PH domain-containing protein 5 antibody, Zinc finger FYVE domain-containing protein 23 antibody

UniProt: Q6ZNL6