Fukutin antibody (AA 87-276) (Biotin)

Catalog No. ABIN7153228

Product Details anti-Fukutin Antibody (Biotin)

Target: Fukutin (FKTN)

Binding Specificity: AA 87-276

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fukutin antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Fukutin protein (87-276AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Fukutin

Target: Fukutin (FKTN)

Alternative Name: FKTN (FKTN Products)

Synonyms: FCMD antibody, fcmd antibody, im:7163166 antibody, zgc:162828 antibody, FKTN antibody, CMD1X antibody, LGMD2M antibody, MDDGA4 antibody, MDDGB4 antibody, MDDGC4 antibody, D830030O17Rik antibody, Fcmd antibody, fukutin antibody, fukutin S homeolog antibody, Fukutin antibody, FKTN antibody, fktn antibody, fktn.S antibody, Bm1_09375 antibody, Bm1_09380 antibody, Bm1_44655 antibody, Fktn antibody

Background:

Background: Glycosyltransferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development.

Aliases: CMD1X antibody, FCMD antibody, FCMD gene antibody, FKTN antibody, FKTN_HUMAN antibody, Fukutin antibody, Fukuyama type congenital muscular dystrophy protein antibody, Fukuyama-type congenital muscular dystrophy protein antibody, LGMD2M antibody, MDDGA4 antibody, MDDGB4 antibody, MDDGC4 antibody, MGC126857 antibody, MGC134944 antibody, MGC134945 antibody, MGC138243 antibody, OTTHUMP00000021841 antibody, patient fukutin antibody

UniProt: O75072

Pathways: Regulation of Carbohydrate Metabolic Process