FOXE3 antibody (AA 4-74) (Biotin)

Catalog No. ABIN7153039

Product Details anti-FOXE3 Antibody (Biotin)

Target: FOXE3 (Forkhead Box E3 (FOXE3))

Binding Specificity: AA 4-74

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXE3 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Forkhead box protein E3 protein (4-74AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FOXE3

Target: FOXE3 (Forkhead Box E3 (FOXE3))

Alternative Name: FOXE3 (FOXE3 Products)

Synonyms: FOXE3 antibody, FKHL12 antibody, FREAC8 antibody, dyl antibody, rct antibody, FREAC-8 antibody, HFH7 antibody, HNF3 antibody, foxe4 antibody, lens1 antibody, lens1-A antibody, forkhead box E3 antibody, forkhead box E3 L homeolog antibody, foxe3 antibody, FOXE3 antibody, LOC100301611 antibody, Foxe3 antibody, foxe3.L antibody

Background:

Background: Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle (PubMed:22527307, PubMed:25504734). During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation (By similarity). Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm (By similarity). Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye (PubMed:27218149).

Aliases: Drosphilia Forkhead Homolog Like 12 antibody, FKHL 12 antibody, FKHL12 antibody, Forkhead Box E3 antibody, Forkhead box protein E3 antibody, Forkhead Related Activator 8 antibody, Forkhead related protein FKHL12 antibody, Forkhead-related protein FKHL12 antibody, Forkhead-related transcription factor 8 antibody, Foxe3 antibody, FOXE3 forkhead box E3 antibody, FOXE3_HUMAN antibody, FREAC 8 antibody, FREAC-8 antibody, FREAC8 antibody

UniProt: Q13461