FPGS antibody (AA 443-546) (HRP)

Catalog No. ABIN7153021

Product Details anti-FPGS Antibody (HRP)

Target: FPGS (Folylpolyglutamate Synthase (FPGS))

Binding Specificity: AA 443-546

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPGS antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Folylpolyglutamate synthase, mitochondrial protein (443-546AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FPGS

Target: FPGS (Folylpolyglutamate Synthase (FPGS))

Alternative Name: FPGS (FPGS Products)

Synonyms: zgc:63807 antibody, wu:fk49h03 antibody, wu:fk51d09 antibody, FPGS antibody, fpgS antibody, SCC88.25c antibody, BA4689 antibody, AA408187 antibody, folylpolyglutamate synthase antibody, dihydrofolate synthase antibody, folylpolyglutamate synthase, mitochondrial antibody, folylpolyglutamyl synthetase antibody, fpgs antibody, fpgS antibody, FPGS antibody, SCO2614 antibody, fgs antibody, folC antibody, CpipJ_CPIJ008043 antibody, Fpgs antibody

Background:

Background: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Unsubstituted reduced folates are the preferred substrates. Metabolizes methotrexate (MTX) to polyglutamates.

Aliases: EC 6.3.2.17 antibody, FOLC antibody, FOLC_HUMAN antibody, Folylpoly gamma glutamate synthetase antibody, Folylpoly-gamma-glutamate synthetase antibody, Folylpolyglutamate synthase antibody, Folylpolyglutamate synthase mitochondrial antibody, FPGS antibody, mitochondrial antibody, OTTHUMP00000022201 antibody, OTTHUMP00000022202 antibody, Tetrahydrofolate synthase antibody, Tetrahydrofolylpolyglutamate synthase antibody

UniProt: Q05932