FOLR2 antibody (AA 35-167)

Catalog No. ABIN7152990

Product Details anti-FOLR2 Antibody

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Binding Specificity: AA 35-167

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOLR2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Folate receptor beta protein (35-167AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FOLR2

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Alternative Name: FOLR2 (FOLR2 Products)

Synonyms: FOLR2 antibody, BETA-HFR antibody, FBP antibody, FBP/PL-1 antibody, FR-BETA antibody, FR-P3 antibody, FBP2 antibody, Folbp-2 antibody, Folbp2 antibody, folate receptor 1 antibody, folate receptor beta antibody, folate receptor 2 (fetal) antibody, FOLR1 antibody, FOLR2 antibody, Folr2 antibody

Background:

Background: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH . Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.

Aliases: beta hFR antibody, FBP antibody, FBP/PL 1 antibody, FBP2 antibody, fetal/placental antibody, folate receptor 2 (fetal) antibody, Folate receptor 2 antibody, Folate receptor antibody, Folate receptor beta antibody, Folate receptor, fetal/placental antibody, Folbp 2 antibody, Folbp2 antibody, Folr2 antibody, FOLR2_HUMAN antibody, FR beta antibody, FR P3 antibody, FR-beta antibody, Placental folate binding protein antibody, Placental folate-binding protein antibody

UniProt: P14207

Pathways: Dicarboxylic Acid Transport