FOLR1 antibody (AA 25-234)

Catalog No. ABIN7152986

Product Details anti-FOLR1 Antibody

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Binding Specificity: AA 25-234

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOLR1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Folate receptor alpha protein (25-234AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FOLR1

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Alternative Name: FOLR1 (FOLR1 Products)

Synonyms: FBP antibody, FOLR antibody, fbp antibody, folr antibody, folr1 antibody, FBP1 antibody, Folbp-1 antibody, Folbp1 antibody, Fbp1 antibody, FOLR1 antibody, Folr1 antibody, folate receptor 1 antibody, folate receptor 1 (adult) antibody, folate receptor 1 (adult) L homeolog antibody, zgc:165502 antibody, Folate receptor alpha antibody, folate receptor alpha antibody, FOLR1 antibody, folr1 antibody, folr1.L antibody, zgc:165502 antibody, Folr1 antibody, LOC100066084 antibody, LOC100725439 antibody

Background:

Background: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH . Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.

Aliases: adult antibody, Adult folate binding protein antibody, Adult folate-binding protein antibody, FBP antibody, Folate Binding Protein antibody, Folate Receptor 1 Adult antibody, Folate receptor 1 antibody, Folate Receptor 1 Precursor antibody, Folate receptor adult antibody, Folate receptor alpha antibody, Folate receptor antibody, FOLR antibody, FOLR1 antibody, FOLR1_HUMAN antibody, FR alpha antibody, FR-alpha antibody, FRalpha antibody, KB cells FBP antibody, MOV18 antibody, Ovarian cancer associated antigen antibody, Ovarian tumor associated antigen antibody, Ovarian tumor associated antigen MOv18 antibody, Ovarian tumor-associated antigen MOv18 antibody

UniProt: P15328

Pathways: Dicarboxylic Acid Transport