Fidgetin antibody (AA 132-371)

Catalog No. ABIN7152932

Product Details anti-Fidgetin Antibody

Target: Fidgetin (FIGN)

Binding Specificity: AA 132-371

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fidgetin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Fidgetin protein (132-371AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Fidgetin

Target: Fidgetin (FIGN)

Alternative Name: FIGN (FIGN Products)

Synonyms: fi antibody, fidget antibody, zgc:110229 antibody, fidgetin, microtubule severing factor antibody, fidgetin antibody, FIGN antibody, fign antibody, Fign antibody

Background:

Background: ATP-dependent microtubule severing protein. Severs microtubules along their length and depolymerizes their ends, primarily the minus-end, that may lead to the suppression of microtubule growth from and attachment to centrosomes. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome.

Aliases: FIGNFidgetin antibody

UniProt: Q5HY92