FCN1 antibody (AA 30-326)

Catalog No. ABIN7152931

Product Details anti-FCN1 Antibody

Target: FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))

Binding Specificity: AA 30-326

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCN1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Ficolin-1 protein (30-326AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FCN1

Target: FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))

Alternative Name: FCN1 (FCN1 Products)

Synonyms: FCNM antibody, FCNB antibody, FCN2 antibody, FCN1 antibody, ficolin 1 antibody, ficolin (collagen/fibrinogen domain containing) 1 antibody, ficolin-1 antibody, FCN1 antibody, Fcn1 antibody, LOC100069029 antibody

Background:

Background: Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8 (PubMed:21037097). Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.

Aliases: Collagen/fibrinogen domain containing protein 1 antibody, Collagen/fibrinogen domain-containing protein 1 antibody, Fcn1 antibody, FCN1_HUMAN antibody, FCNM antibody, ficolin (collagen/fibrinogen domain containing) 1 antibody, Ficolin 1 antibody, Ficolin A antibody, Ficolin alpha antibody, Ficolin-1 antibody, Ficolin-A antibody, Ficolin-alpha antibody, M ficolin antibody, M-ficolin antibody

UniProt: O00602

Pathways: Complement System