FERMT3 antibody (AA 388-503)

Catalog No. ABIN7152706

Product Details anti-FERMT3 Antibody

Target: FERMT3 (Fermitin Family Member 3 (FERMT3))

Binding Specificity: AA 388-503

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FERMT3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Fermitin family homolog 3 protein (388-503AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FERMT3

Target: FERMT3 (Fermitin Family Member 3 (FERMT3))

Alternative Name: FERMT3 (FERMT3 Products)

Synonyms: C79673 antibody, Kindlin3 antibody, RGD1310168 antibody, MGC69069 antibody, MGC88900 antibody, KIND3 antibody, MIG-2 antibody, MIG2B antibody, UNC112C antibody, URP2 antibody, URP2SF antibody, zgc:64101 antibody, fermitin family member 3 antibody, fermitin family member 3 L homeolog antibody, fermitin family member 3b antibody, Fermt3 antibody, fermt3.L antibody, fermt3 antibody, FERMT3 antibody, fermt3b antibody

Background:

Background: Plays a central role in cell adhesion in hematopoietic cells (PubMed:19234463, PubMed:26359933). Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) (By similarity). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed:19234460). Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity).

Aliases: Fermitin family homolog 3 antibody, Fermitin family member 3 antibody, FERMT3 antibody, Kind3 antibody, Kindlin 3 antibody, Kindlin-3 antibody, Kindlin3 antibody, MGC10966 antibody, MIG 2 antibody, MIG2 like protein antibody, MIG2-like protein antibody, MIG2B antibody, Unc 112 related protein 2 antibody, Unc-112-related protein 2 antibody, UNC112C antibody, URP2 antibody, URP2_HUMAN antibody, URP2SF antibody

UniProt: Q86UX7