FARP2 antibody (AA 261-550)

Catalog No. ABIN7152694

Product Details anti-FARP2 Antibody

Target: FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))

Binding Specificity: AA 261-550

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FARP2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human FERM, ARHGEF and pleckstrin domain-containing protein 2 protein (261-550AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FARP2

Target: FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))

Alternative Name: FARP2 (FARP2 Products)

Synonyms: FARP2 antibody, wu:fc23d05 antibody, wu:fp25d09 antibody, MGC131000 antibody, FIR antibody, FRG antibody, PLEKHC3 antibody, AI465173 antibody, BC009153 antibody, D030026M03Rik antibody, Fir antibody, mKIAA0793 antibody, FERM, ARH/RhoGEF and pleckstrin domain protein 2 antibody, FERM, RhoGEF and pleckstrin domain protein 2 antibody, FERM, ARH/RhoGEF and pleckstrin domain protein 2 L homeolog antibody, FARP2 antibody, farp2 antibody, farp2.L antibody, Farp2 antibody

Background:

Background: Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity).

Aliases: FARP2 antibody, FARP2_HUMAN antibody, FERM antibody, FERM domain including RhoGEF antibody, FERM, RhoGEF and pleckstrin domain protein 2 antibody, FERM, RhoGEF and pleckstrin domain-containing protein 2 antibody, FGD1 related Cdc42 GEF antibody, FIR antibody, FRG antibody, KIAA0793 antibody, PH domain-containing family C member 3 antibody, Pleckstrin homology domain-containing family C member 3 antibody, PLEKHC3 antibody, RhoGEF and pleckstrin domain protein 2 antibody, RhoGEF and pleckstrin domain-containing protein 2 antibody

UniProt: O94887