FADS1 antibody (AA 1-121)

Catalog No. ABIN7152606

Product Details anti-FADS1 Antibody

Target: FADS1 (Fatty Acid Desaturase 1 (FADS1))

Binding Specificity: AA 1-121

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FADS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Fatty acid desaturase 1 protein (1-121AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FADS1

Target: FADS1 (Fatty Acid Desaturase 1 (FADS1))

Alternative Name: FADS1 (FADS1 Products)

Synonyms: D5D antibody, FADS6 antibody, FADSD5 antibody, LLCDL1 antibody, TU12 antibody, D5FAD antibody, 0710001O03Rik antibody, A930006B21Rik antibody, AI317215 antibody, DSD antibody, fatty acid desaturase 1 antibody, FADS1 antibody, LOC483793 antibody, Fads1 antibody

Background:

Background: Isoform 2 does not exhibit any catalytic activity toward 20:3n-6, but it may enhance FADS2 activity (By similarity). Isoform 1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3), respectively.

Aliases: D5D antibody, Delta 5 desaturase antibody, Delta 5 fatty acid desaturase antibody, Delta(5) desaturase antibody, Delta(5) fatty acid desaturase antibody, Delta-5 desaturase antibody, Fads1 antibody, FADS1_HUMAN antibody, FADS6 antibody, FADSD5 antibody, Fatty acid desaturase 1 antibody, FLJ38956 antibody, Linoleoyl CoA desaturase (delta 6 desaturase) like 1 antibody, LLCDL1 antibody, TU12 antibody

UniProt: O60427

Pathways: Regulation of Lipid Metabolism by PPARalpha