FAIM3 antibody (AA 18-251)

Catalog No. ABIN7152579

Product Details anti-FAIM3 Antibody

Target: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Binding Specificity: AA 18-251

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAIM3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Fas apoptotic inhibitory molecule 3 protein (18-251AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FAIM3

Target: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Alternative Name: FCMR (FAIM3 Products)

Synonyms: FAIM3 antibody, FCMR antibody, TOSO antibody, 1810037B05Rik antibody, FcmuR antibody, Toso antibody, Fc fragment of IgM receptor antibody, FCMR antibody, Fcmr antibody

Background:

Background: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Aliases: Faim3 antibody, FAIM3_HUMAN antibody, Fas apoptotic inhibitory molecule 3 antibody, Fc fragment of IgM receptor antibody, Fc mu receptor antibody, FCMR antibody, IgM Fc receptor antibody, Immunoglobulin mu Fc receptor antibody, Regulator of Fas induced apoptosis antibody, Regulator of Fas-induced apoptosis Toso antibody, TOSO antibody

UniProt: O60667