FANCI antibody (AA 180-252) (Biotin)

Catalog No. ABIN7152558

Product Details anti-FANCI Antibody (Biotin)

Target: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Binding Specificity: AA 180-252

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCI antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Fanconi anemia group I protein (180-252AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FANCI

Target: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Alternative Name: FANCI (FANCI Products)

Synonyms: KIAA1794 antibody, Fanconi anemia complementation group I antibody, Fanconi anemia, complementation group I antibody, FANCI antibody, Fanci antibody

Background:

Background: Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA: binds both single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage.

Aliases: FANCI antibody, FANCI gene antibody, FANCI_HUMAN antibody, Fanconi anemia group I protein antibody, Fanconi anemia, complementation group I antibody, FLJ10719 antibody, FLJ14658 antibody, KIAA1794 antibody, Protein FACI antibody, Protein FANCI antibody

UniProt: Q9NVI1

Pathways: DNA Damage Repair