BTRC antibody (AA 701-1000)

Catalog No. ABIN7152486

Product Details anti-BTRC Antibody

Target: BTRC (beta-Transducin Repeat Containing (BTRC))

Binding Specificity: AA 701-1000

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTRC antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human F-box/WD repeat-containing protein 10 protein (701-1000AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BTRC

Target: BTRC (beta-Transducin Repeat Containing (BTRC))

Alternative Name: FBXW1 (BTRC Products)

Synonyms: BTRC antibody, Beta-TrCP antibody, betaTrCP antibody, btrcp antibody, btrcp1 antibody, fbw1a antibody, fbxw1 antibody, fbxw1a antibody, fwd1 antibody, btrc antibody, beta-TrCP antibody, BETA-TRCP antibody, FBW1A antibody, FBXW1 antibody, FBXW1A antibody, FWD1 antibody, bTrCP antibody, bTrCP1 antibody, beta-TrCP1 antibody, btrc-a antibody, Beta-Trcp1 antibody, Fbw1a antibody, HOS antibody, Slimb antibody, b-TrCP antibody, mKIAA4123 antibody, beta-transducin repeat containing E3 ubiquitin protein ligase antibody, beta-transducin repeat containing antibody, beta-TrCP antibody, beta-transducin repeat containing E3 ubiquitin protein ligase S homeolog antibody, beta-transducin repeat containing protein antibody, BTRC antibody, btrc antibody, LOC100634006 antibody, Btrc antibody, btrc.S antibody

Background:

Background: Probable substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1.

Aliases: FBXW10 antibody, F-box/WD repeat-containing protein 10 antibody, F-box and WD-40 domain-containing protein 10 antibody, Ubiquitin ligase-specificity factor antibody

UniProt: Q5XX13

Pathways: Cell Division Cycle, Hedgehog Signaling