FBXL5 antibody (AA 1-310)
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- Target See all FBXL5 Antibodies
- FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))
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Binding Specificity
- AA 1-310
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FBXL5 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), ELISA
- Cross-Reactivity
- Human
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human F-box/LRR-repeat protein 5 protein (1-310AA)
- Isotype
- IgG
- Top Product
- Discover our top product FBXL5 Primary Antibody
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))
- Alternative Name
- FBXL5 (FBXL5 Products)
- Synonyms
- fbxl5 antibody, MGC53238 antibody, FBXL5 antibody, FBL4 antibody, FBL5 antibody, FLR1 antibody, Fbl4 antibody, Fir4 antibody, wu:fb52d06 antibody, F-box and leucine rich repeat protein 5 antibody, F-box and leucine-rich repeat protein 5 S homeolog antibody, F-box and leucine-rich repeat protein 5 L homeolog antibody, F-box and leucine-rich repeat protein 5 antibody, FBXL5 antibody, fbxl5.S antibody, fbxl5.L antibody, fbxl5 antibody, Fbxl5 antibody
- Background
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Background: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.
Aliases: F box and leucine rich repeat protein 5 antibody, F box protein FBL5 antibody, F box/LRR repeat protein 5 antibody, F-box and leucine-rich repeat protein 5 antibody, F-box protein FBL4/FBL5 antibody, F-box/LRR-repeat protein 5 antibody, FBL4 antibody, FBL5 antibody, FBXL5 antibody, FBXL5_HUMAN antibody, FLR1 antibody, p45SKP2 like protein antibody, p45SKP2-like protein antibody
- UniProt
- Q9UKA1
- Pathways
- Transition Metal Ion Homeostasis
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