Cyclin F antibody (AA 248-400) (HRP)

Catalog No. ABIN7152405

Product Details anti-Cyclin F Antibody (HRP)

Target: Cyclin F (CCNF)

Binding Specificity: AA 248-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin F antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human F-box only protein 10 protein (248-400AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Cyclin F

Target: Cyclin F (CCNF)

Alternative Name: FBXO1 (CCNF Products)

Synonyms: Cyclin-F antibody, DKFZp459P0432 antibody, FBX1 antibody, FBXO1 antibody, CycF antibody, Fbxo1 antibody, cb443 antibody, zgc:77240 antibody, cyclin F antibody, cyclin F L homeolog antibody, CCNF antibody, ccnf.L antibody, ccnf antibody, Ccnf antibody

Background:

Background: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. The SCF(FBXO10) complex mediates ubiquitination and degradation of BCL2, an antiapoptotic protein, thereby playing a role in apoptosis by controlling the stability of BCL2.

Aliases: F box protein 10 antibody, F-box only protein 10 antibody, FBX10 antibody, FBX10_HUMAN antibody, Fbxo10 antibody, hCG_2011110 antibody, PRMT11 antibody

UniProt: Q9UK96