FCHO2 antibody (AA 100-203) (Biotin)

Catalog No. ABIN7152395

Product Details anti-FCHO2 Antibody (Biotin)

Target: FCHO2 (FCH Domain Only 2 (FCHO2))

Binding Specificity: AA 100-203

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCHO2 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human F-BAR domain only protein 2 protein (100-203AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FCHO2

Target: FCHO2 (FCH Domain Only 2 (FCHO2))

Alternative Name: FCHO2 (FCHO2 Products)

Synonyms: 5832424M12Rik antibody, AA387320 antibody, RGD1565396 antibody, cb304 antibody, sb:cb304 antibody, wu:fa01a02 antibody, zgc:112167 antibody, FCH domain only 2 antibody, FCHO2 antibody, fcho2 antibody, Fcho2 antibody

Background:

Background: Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.

Aliases: FCHO2F-BAR domain only protein 2 antibody

UniProt: Q0JRZ9