EXTL3 antibody (AA 2-245) (HRP)

Catalog No. ABIN7152316

Product Details anti-EXTL3 Antibody (HRP)

Target: EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

Binding Specificity: AA 2-245

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXTL3 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Exostosin-like 3 protein (2-245AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for EXTL3

Target: EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

Alternative Name: EXTL3 (EXTL3 Products)

Background:

Background: Glycosyltransferase which regulates the biosynthesis of heparan sulfate (HS). Important for both skeletal development and hematopoiesis, through the formation of HS proteoglycans (HSPGs) (PubMed:28132690, PubMed:28148688). Required for the function of REG3A in regulating keratinocyte proliferation and differentiation (PubMed:22727489).

Aliases: botv antibody, DKFZp686C2342 antibody, Exostoses (multiple)-like 3 antibody, Exostoses-like 3 antibody, Exostosin-like 3 antibody, EXT-related protein 1 antibody, EXTL1L antibody, EXTL3 antibody, EXTL3_HUMAN antibody, EXTR1 antibody, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferas antibody, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody, Hereditary multiple exostoses gene isolog antibody, KIAA0519 antibody, Multiple exostosis-like protein 3 antibody, Putative tumor suppressor protein EXTL3 antibody, REG antibody, Reg receptor antibody, REGR antibody, RPR antibody

UniProt: O43909

Pathways: Glycosaminoglycan Metabolic Process, ER-Nucleus Signaling