EXTL3 antibody (AA 2-245) (Biotin)

Catalog No. ABIN7152314

Product Details anti-EXTL3 Antibody (Biotin)

Target: EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

Binding Specificity: AA 2-245

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXTL3 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Exostosin-like 3 protein (2-245AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for EXTL3

Target: EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

Alternative Name: EXTL3 (EXTL3 Products)

Synonyms: BcDNA:LD21192 antibody, Botv antibody, CG15110 antibody, DEXT3 antibody, DEXTL3 antibody, Dextl3 antibody, Dmel\\CG15110 antibody, Extl3 antibody, 2900009G18Rik antibody, AU040105 antibody, Ext1l antibody, mKIAA0519 antibody, BOTV antibody, EXTL1L antibody, EXTR1 antibody, REGR antibody, RPR antibody, Regr antibody, brother of tout-velu antibody, exostoses (multiple)-like 3 antibody, exostosin like glycosyltransferase 3 antibody, exostosin-like glycosyltransferase 3 antibody, botv antibody, Extl3 antibody, EXTL3 antibody

Background:

Background: Glycosyltransferase which regulates the biosynthesis of heparan sulfate (HS). Important for both skeletal development and hematopoiesis, through the formation of HS proteoglycans (HSPGs) (PubMed:28132690, PubMed:28148688). Required for the function of REG3A in regulating keratinocyte proliferation and differentiation (PubMed:22727489).

Aliases: botv antibody, DKFZp686C2342 antibody, Exostoses (multiple)-like 3 antibody, Exostoses-like 3 antibody, Exostosin-like 3 antibody, EXT-related protein 1 antibody, EXTL1L antibody, EXTL3 antibody, EXTL3_HUMAN antibody, EXTR1 antibody, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferas antibody, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody, Hereditary multiple exostoses gene isolog antibody, KIAA0519 antibody, Multiple exostosis-like protein 3 antibody, Putative tumor suppressor protein EXTL3 antibody, REG antibody, Reg receptor antibody, REGR antibody, RPR antibody

UniProt: O43909

Pathways: Glycosaminoglycan Metabolic Process, ER-Nucleus Signaling