EXT2 antibody (AA 180-267) (HRP)

Catalog No. ABIN7152312

Product Details anti-EXT2 Antibody (HRP)

Target: EXT2 (Exostosin 2 (EXT2))

Binding Specificity: AA 180-267

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXT2 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Exostosin-2 protein (180-267AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for EXT2

Target: EXT2 (Exostosin 2 (EXT2))

Alternative Name: EXT2 (EXT2 Products)

Synonyms: SOTV antibody, AI893565 antibody, EXT2 antibody, ext2 antibody, exostosin glycosyltransferase 2 antibody, exostoses (multiple) 2 antibody, exostoses (multiple) 3 antibody, exostosin glycosyltransferase 2 L homeolog antibody, EXT2 antibody, Ext2 antibody, EXT3 antibody, ext2.L antibody

Background:

Background: Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).

Aliases: Exostoses (multiple) 2 antibody, Exostosin 2 antibody, Exostosin-2 antibody, EXT2 antibody, EXT2_HUMAN antibody, Glucuronosyl N acetylglucosaminyl proteoglycan 4 alpha N acetylglucosaminyltransferase antibody, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody, Multiple exostoses protein 2 antibody, N acetylglucosaminyl proteoglycan 4 beta glucuronosyltransferase antibody, Putative tumor suppressor protein EXT2 antibody, SOTV antibody

UniProt: Q93063

Pathways: Glycosaminoglycan Metabolic Process