EXT1 antibody (AA 28-171) (Biotin)

Catalog No. ABIN7152306

Product Details anti-EXT1 Antibody (Biotin)

Target: EXT1 (Exostosin 1 (EXT1))

Binding Specificity: AA 28-171

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXT1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Exostosin-1 protein (28-171AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for EXT1

Target: EXT1 (Exostosin 1 (EXT1))

Alternative Name: EXT1 (EXT1 Products)

Synonyms: EXT antibody, LGCR antibody, LGS antibody, TRPS2 antibody, TTV antibody, AA409028 antibody, xext1 antibody, fd07d06 antibody, wu:fd07d06 antibody, exostosin glycosyltransferase 1 antibody, exostoses (multiple) 1 antibody, exostosin glycosyltransferase 1b antibody, exostosin like glycosyltransferase 1 antibody, exostosin glycosyltransferase 1 S homeolog antibody, exostosin glycosyltransferase 1a antibody, EXT1 antibody, Ext1 antibody, ext1b antibody, EXTL1 antibody, ext1.S antibody, ext1a antibody

Background:

Background: Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).

Aliases: 4-alpha-N-acetylglucosaminyltransferase antibody, exostoses (multiple) 1 antibody, Exostosin 1 antibody, Exostosin glycosyltransferase 1 antibody, Exostosin-1 antibody, EXT antibody, EXT1 antibody, EXT1_HUMAN antibody, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody, glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan antibody, Langer-Giedion syndrome chromosome region antibody, LGCR antibody, LGS antibody, Multiple exostoses protein 1 antibody, Multiple exostoses protein 1 homolog antibody, N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase antibody, Putative tumor suppressor protein EXT1 antibody, TRPS2 antibody, TTV antibody

UniProt: Q16394

Pathways: Glycosaminoglycan Metabolic Process