EXD2 antibody (AA 137-245) (Biotin)

Catalog No. ABIN7152270

Product Details anti-EXD2 Antibody (Biotin)

Target: EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))

Binding Specificity: AA 137-245

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXD2 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Exonuclease 3\\\'-5\\\' domain-containing protein 2 protein (137-245AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for EXD2

Target: EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))

Alternative Name: EXD2 (EXD2 Products)

Synonyms: C14orf114 antibody, EXDL2 antibody, 4930539P14Rik antibody, C85658 antibody, Exdl2 antibody, RGD1311087 antibody, exd2-b antibody, exdl2 antibody, fi72h12 antibody, wu:fi72h12 antibody, zgc:175195 antibody, exd2 antibody, exd2-a antibody, exonuclease 3'-5' domain containing 2 antibody, exonuclease 3'-5' domain containing 2 b antibody, EXD2 antibody, Exd2 antibody, exd2.S antibody, exd2 antibody, exd2.L antibody

Background:

Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3\\\'-5\\\' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

Aliases: 4930539P14Rik antibody, C14orf114 antibody, C85658 antibody, DKFZp781A0133 antibody, DKFZp781L15100 antibody, Exd2 antibody, EXD2_HUMAN antibody, EXDL2 antibody, Exonuclease 3''-5'' domain-containing protein 2 antibody, Exonuclease 3''-5'' domain-like-containing protein 2 antibody, exonuclease 3'-5' domain-like 2 antibody, FLJ10738 antibody, RGD1311087 antibody

UniProt: Q9NVH0