EIF4E antibody (AA 2-217)

Catalog No. ABIN7152184

Product Details anti-EIF4E Antibody

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Binding Specificity: AA 2-217

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF4E antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Eukaryotic translation initiation factor 4E protein (2-217AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for EIF4E

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Alternative Name: EIF4E (EIF4E Products)

Background:

Background: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.

Aliases: AUTS19 antibody, CBP antibody, eIF 4E antibody, eIF 4F 25 kDa subunit antibody, EIF 4F antibody, eIF-4E antibody, eIF-4F 25 kDa subunit antibody, eIF4E antibody, EIF4E1 antibody, EIF4EL1 antibody, EIF4F antibody, Eukaryotic translation initiation factor 4 E antibody, Eukaryotic translation initiation factor 4E antibody, Eukaryotic translation initiation factor 4E like 1 antibody, IF4E_HUMAN antibody, Messanger RNA Cap Binding Protein eIF 4E antibody, MGC111573 antibody, mRNA cap binding protein antibody, mRNA cap-binding protein antibody

UniProt: P06730

Pathways: BCR Signaling