EIF3H antibody (AA 80-340)

Catalog No. ABIN7152160

Product Details anti-EIF3H Antibody

Target: EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))

Binding Specificity: AA 80-340

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3H antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Rat

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Eukaryotic translation initiation factor 3 subunit H protein (80-340AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for EIF3H

Target: EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))

Alternative Name: EIF3H (EIF3H Products)

Background:

Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Aliases: eIF-3-gamma antibody, eIF3 gamma antibody, eIF3 p40 antibody, eIF3 p40 subunit antibody, eIF3h antibody, EIF3H_HUMAN antibody, EIF3S3 antibody, Eukaryotic translation initiation factor 3 subunit 3 antibody, Eukaryotic translation initiation factor 3 subunit H antibody, MGC102958 antibody

UniProt: O15372

Pathways: Ribonucleoprotein Complex Subunit Organization