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EIF3A antibody (AA 1288-1379)

EIF3A Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7152145
  • Target See all EIF3A Antibodies
    EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
    Binding Specificity
    • 10
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1288-1379
    Reactivity
    • 41
    • 19
    • 14
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 39
    • 3
    Rabbit
    Clonality
    • 40
    • 2
    Polyclonal
    Conjugate
    • 21
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EIF3A antibody is un-conjugated
    Application
    • 30
    • 19
    • 19
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Eukaryotic translation initiation factor 3 subunit A protein (1288-1379AA)
    Isotype
    IgG
    Top Product
    Discover our top product EIF3A Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
    Alternative Name
    EIF3A (EIF3A Products)
    Synonyms
    EIF3 antibody, EIF3S10 antibody, P167 antibody, TIF32 antibody, eIF3-p170 antibody, eIF3-theta antibody, p180 antibody, p185 antibody, EIF6 antibody, A830012B05Rik antibody, Csma antibody, Eif3 antibody, Eif3s10 antibody, mKIAA0139 antibody, ZH12 antibody, eif3s10 antibody, eIF3 p110 antibody, eIF3a antibody, eukaryotic translation initiation factor 3 subunit A antibody, eukaryotic translation initiation factor 3, subunit A antibody, eukaryotic translation initiation factor 3 subunit A S homeolog antibody, translation initiation factor eIF3a antibody, EIF3A antibody, Eif3a antibody, eif3a.S antibody, tif32 antibody
    Background

    Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Essential for the initiation of translation on type-1 viral ribosomal entry sites (IRESs), like for HCV, PV, EV71 or BEV translation (PubMed:23766293, PubMed:24357634). In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426).

    Aliases: centrosomin homolog antibody, cytoplasmic protein p167 antibody, eIF 3 theta antibody, eIF-3-theta antibody, EIF3 antibody, eIF3 p167 antibody, eIF3 p170 antibody, eIF3 p180 antibody, EIF3 p180 subunit antibody, eIF3 p185 antibody, eIF3 theta antibody, eIF3a antibody, EIF3A_HUMAN antibody, EIF3S10 antibody, eukaryotic translation initiation factor 3 subunit 10 (theta 150 170kD) antibody, eukaryotic translation initiation factor 3 subunit 10 (theta 170kD) antibody, eukaryotic translation initiation factor 3 subunit 10 170 kDa antibody, Eukaryotic translation initiation factor 3 subunit 10 antibody, eukaryotic translation initiation factor 3 subunit 10 theta 150 170 kDa antibody, Eukaryotic translation initiation factor 3 subunit A antibody, OTTHUMP00000020589 antibody, P167 antibody, p180 antibody, p185 antibody, TIF32 antibody

    UniProt
    Q14152
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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