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EIF3A antibody (AA 1288-1379)

EIF3A Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7152145
  • Target See all EIF3A Antibodies
    EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
    Binding Specificity
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1288-1379
    Reactivity
    • 36
    • 19
    • 14
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 34
    • 3
    Rabbit
    Clonality
    • 35
    • 2
    Polyclonal
    Conjugate
    • 21
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EIF3A antibody is un-conjugated
    Application
    • 25
    • 14
    • 14
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Eukaryotic translation initiation factor 3 subunit A protein (1288-1379AA)
    Isotype
    IgG
    Top Product
    Discover our top product EIF3A Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
    Alternative Name
    EIF3A (EIF3A Products)
    Background

    Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Essential for the initiation of translation on type-1 viral ribosomal entry sites (IRESs), like for HCV, PV, EV71 or BEV translation (PubMed:23766293, PubMed:24357634). In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426).

    Aliases: centrosomin homolog antibody, cytoplasmic protein p167 antibody, eIF 3 theta antibody, eIF-3-theta antibody, EIF3 antibody, eIF3 p167 antibody, eIF3 p170 antibody, eIF3 p180 antibody, EIF3 p180 subunit antibody, eIF3 p185 antibody, eIF3 theta antibody, eIF3a antibody, EIF3A_HUMAN antibody, EIF3S10 antibody, eukaryotic translation initiation factor 3 subunit 10 (theta 150 170kD) antibody, eukaryotic translation initiation factor 3 subunit 10 (theta 170kD) antibody, eukaryotic translation initiation factor 3 subunit 10 170 kDa antibody, Eukaryotic translation initiation factor 3 subunit 10 antibody, eukaryotic translation initiation factor 3 subunit 10 theta 150 170 kDa antibody, Eukaryotic translation initiation factor 3 subunit A antibody, OTTHUMP00000020589 antibody, P167 antibody, p180 antibody, p185 antibody, TIF32 antibody

    UniProt
    Q14152
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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