Elf4 antibody (AA 1-200)
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- Target See all Elf4 Antibodies
- Elf4 (E74 like ETS transcription factor 4 (Elf4))
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Binding Specificity
- AA 1-200
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Elf4 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human ETS-related transcription factor Elf-4 protein (1-200AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Elf4 (E74 like ETS transcription factor 4 (Elf4))
- Alternative Name
- ELF4 (Elf4 Products)
- Synonyms
- ELF4 antibody, RGD1560743 antibody, ELFR antibody, MEF antibody, AV314029 antibody, BC042423 antibody, ENSMUSG00000053512 antibody, Gm9907 antibody, Mef antibody, E74 like ETS transcription factor 4 antibody, E74-like factor 4 (ets domain transcription factor) antibody, ELF4 antibody, Elf4 antibody
- Background
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Background: Transcriptional activator that binds to DNA sequences containing the consensus 5\\\'-WGGA-3\\\'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity). Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway.
Aliases: E74-like factor 4 antibody, ELF4 antibody, ELF4_HUMAN antibody, ELFR antibody, ETS-related transcription factor Elf-4 antibody, ETS-related transcription factor Elf4 antibody, MEF antibody, Myeloid Elf-1-like factor antibody, Myeloid Elf1-like factor antibody
- UniProt
- Q99607
- Pathways
- Positive Regulation of Endopeptidase Activity
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