ERLIN1 antibody (AA 27-346)

Catalog No. ABIN7151992

Product Details anti-ERLIN1 Antibody

Target: ERLIN1 (ER Lipid Raft Associated 1 (ERLIN1))

Binding Specificity: AA 27-346

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERLIN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Erlin-1 protein (27-346AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ERLIN1

Target: ERLIN1 (ER Lipid Raft Associated 1 (ERLIN1))

Alternative Name: ERLIN1 (ERLIN1 Products)

Synonyms: C10orf69 antibody, Erlin-1 antibody, KE04 antibody, KEO4 antibody, SPFH1 antibody, wu:fa10h05 antibody, wu:fb19h05 antibody, zgc:110547 antibody, 2810439N09Rik antibody, C80197 antibody, Keo4 antibody, Spfh1 antibody, RGD1307058 antibody, erlin-1 antibody, ER lipid raft associated 1 antibody, ERLIN1 antibody, erlin1 antibody, Erlin1 antibody

Background:

Background: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex (PubMed:24217618).

Aliases: Band 7 23-211 Keo4 (Interim) similar to C.elegans protein antibody, C10orf69 antibody, chromosome 10 open reading frame 69 antibody, Endoplasmic reticulum lipid raft-associated protein 1 antibody, ER lipid raft associated 1 antibody, Erlin 1 antibody, Erlin-1 antibody, ERLIN1 antibody, ERLN1_HUMAN antibody, KE04 antibody, KEO4 antibody, OTTHUMP00000059425 antibody, Protein KE04 antibody, SPFH domain containing protein 1 antibody, SPFH domain family, member 1 antibody, SPFH domain-containing protein 1 antibody, SPFH1 antibody, SPG62 antibody, Stomatin-prohibitin-flotillin-HflC/K domain containing protein 1 antibody, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1 antibody

UniProt: O75477