Ephrin B2 antibody (AA 28-229)

Catalog No. ABIN7151879

Product Details anti-Ephrin B2 Antibody

Target: Ephrin B2 (EFNB2)

Binding Specificity: AA 28-229

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ephrin B2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Ephrin-B2 protein (28-229AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Ephrin B2

Target: Ephrin B2 (EFNB2)

Alternative Name: EFNB2 (EFNB2 Products)

Synonyms: EFNB2 antibody, efnb2 antibody, ephrin-B2 antibody, htkl antibody, eplg5 antibody, htk-l antibody, lerk5 antibody, ephrinB2 antibody, efnb2a antibody, MGC68890 antibody, efnb2b antibody, ELF-2 antibody, Epl5 antibody, Eplg5 antibody, Htk-L antibody, LERK-5 antibody, Lerk5 antibody, NLERK-1 antibody, EPLG5 antibody, HTKL antibody, LERK5 antibody, ephrin B2 antibody, ephrin-B2 precursor antibody, ephrin B2 L homeolog antibody, ephrin B2 S homeolog antibody, EFNB2 antibody, efnb2 antibody, efnb2.L antibody, efnb2.S antibody, Efnb2 antibody

Background:

Background: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.

Aliases: EFN B2 antibody, EFNB 2 antibody, Efnb2 antibody, EFNB2_HUMAN antibody, Eph related receptor tyrosine kinase ligand 5 antibody, EPH-related receptor tyrosine kinase ligand 5 antibody, ephrin B2 antibody, Ephrin-B2 antibody, EphrinB2 antibody, EPLG 5 antibody, EPLG5 antibody, Htk L antibody, HTK ligand antibody, HTK-L antibody, HTKL antibody, LERK 5 antibody, LERK-5 antibody, LERK5 antibody, Ligand of eph related kinase 5 antibody, MGC126226 antibody, MGC126227 antibody, MGC126228 antibody, OTTMUSP00000024973 antibody

UniProt: P52799

Pathways: RTK Signaling, Regulation of Muscle Cell Differentiation