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NGEF antibody (AA 495-710) (FITC)

NGEF Reactivity: Human Host: Rabbit Polyclonal FITC
Catalog No. ABIN7151825
  • Target See all NGEF Antibodies
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    Binding Specificity
    • 15
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 495-710
    Reactivity
    • 41
    • 41
    • 33
    • 3
    • 3
    • 3
    • 3
    Human
    Host
    • 47
    • 1
    Rabbit
    Clonality
    • 47
    • 1
    Polyclonal
    Conjugate
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NGEF antibody is conjugated to FITC
    Application
    Please inquire
    Cross-Reactivity
    Human
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Ephexin-1 protein (495-710AA)
    Isotype
    IgG
    Top Product
    Discover our top product NGEF Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    Alternative Name
    NGEF (NGEF Products)
    Synonyms
    Ephexin-1 antibody, ARHGEF27 antibody, EPHEXIN antibody, Tims2 antibody, ephexin antibody, Besh3 antibody, ephexin-1 antibody, neuronal guanine nucleotide exchange factor antibody, NGEF antibody, Ngef antibody
    Background

    Background: Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).

    Aliases: ARHGEF27 antibody, Eph receptor-interacting exchange protein antibody, Eph-interacting exchange protein antibody, EPHEXIN antibody, Ephexin-1 antibody, Guanine nucleotide exchange factor, neuronal antibody, Neuronal guanine nucleotide exchange factor antibody, Ngef antibody, NGEF_HUMAN antibody

    UniProt
    Q8N5V2
    Pathways
    Neurotrophin Signaling Pathway
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