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Genome Polyprotein (LOC100493440) (AA 566-862) antibody (HRP)

LOC100493440 Reactivity: Human Enterovirus 71 ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN7151809
  • Target See all Genome Polyprotein (LOC100493440) Antibodies
    Genome Polyprotein (LOC100493440)
    Binding Specificity
    • 9
    • 6
    • 4
    AA 566-862
    Reactivity
    • 9
    • 5
    • 5
    • 5
    • 4
    Human Enterovirus 71
    Host
    • 28
    Rabbit
    Clonality
    • 28
    Polyclonal
    Conjugate
    • 10
    • 7
    • 6
    • 5
    HRP
    Application
    • 24
    • 3
    ELISA
    Cross-Reactivity
    Human Enterovirus 71
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human enterovirus 71 Genome polyprotein protein (566-862AA)
    Isotype
    IgG
    Top Product
    Discover our top product LOC100493440 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Genome Polyprotein (LOC100493440)
    Alternative Name
    Genome polyprotein (LOC100493440 Products)
    Synonyms
    JEV polyprotein antibody, polyprotein precursor antibody, Genome polyprotein antibody, flavivirus polyprotein gene antibody, YFVgp1 antibody
    Target Type
    Viral Protein
    Background

    Background: Capsid protein VP1: Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome. Capsid protein VP1 mainly forms the vertices of the capsid. Capsid protein VP1 interacts with host cell receptor to provide virion attachment to target host cells. This attachment induces virion internalization. Tyrosine kinases are probably involved in the entry process. After binding to its receptor, the capsid undergoes conformational changes. Capsid protein VP1 N-terminus (that contains an amphipathic alpha-helix) and capsid protein VP4 are externalized. Together, they shape a pore in the host membrane through which viral genome is translocated to host cell cytoplasm. After genome has been released, the channel shrinks.

    Aliases: antibody, Genome polyprotein [Cleaved into: P1, Capsid protein VP0 antibody, VP4-VP2), Capsid protein VP4 antibody, P1A antibody, Virion protein 4), Capsid protein VP2 antibody, P1B antibody, Virion protein 2), Capsid protein VP3 antibody, P1C antibody, Virion protein 3), Capsid protein VP1 antibody, P1D antibody, Virion protein 1), P2, Protease 2A antibody, P2A antibody, EC 3.4.22.29 antibody, Picornain 2A antibody, Protein 2A), Protein 2B antibody, P2B), Protein 2C antibody, P2C antibody, EC 3.6.1.15), P3, Protein 3AB, Protein 3A antibody, P3A), Viral protein genome-linked antibody, VPg antibody, Protein 3B antibody, P3B), Protein 3CD antibody, EC 3.4.22.28), Protease 3C antibody, EC 3.4.22.28 antibody, Picornain 3C antibody, P3C), RNA-directed RNA polymerase antibody, RdRp antibody, EC 2.7.7.48 antibody, 3D polymerase antibody, 3Dpol antibody, Protein 3D antibody, 3D)] antibody

    UniProt
    Q66478
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