MIA2 antibody (AA 515-632)

Catalog No. ABIN7151667

Product Details anti-MIA2 Antibody

Target: MIA2 (Melanoma Inhibitory Activity Protein 2 (MIA2))

Binding Specificity: AA 515-632

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MIA2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Endoplasmic reticulum export factor CTAGE5 protein (515-632AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MIA2

Target: MIA2 (Melanoma Inhibitory Activity Protein 2 (MIA2))

Alternative Name: CTAGE5 (MIA2 Products)

Synonyms: MEA6 antibody, MGEA antibody, MGEA11 antibody, MGEA6 antibody, zgc:56047 antibody, melanoma inhibitory activity 2 antibody, CTAGE family, member 5 antibody, CTAGE family member 5, ER export factor antibody, MIA2 antibody, ctage5 antibody, CTAGE5 antibody, Mia2 antibody

Background:

Background: Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites.

Aliases: Endoplasmic reticulum export factor CTAGE5 (CTAGE family member 5 ER export factor) (Protein cTAGE-5) (Meningioma-expressed antigen 6/11), CTAGE5, MEA11 MEA6 MGEA11 MGEA6

UniProt: O15320