ELOVL1 antibody (AA 82-175)

Catalog No. ABIN7151556

Product Details anti-ELOVL1 Antibody

Target: ELOVL1 (ELOVL Fatty Acid Elongase 1 (ELOVL1))

Binding Specificity: AA 82-175

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELOVL1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Elongation of very long chain fatty acids protein 1 protein (82-175AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ELOVL1

Target: ELOVL1 (ELOVL Fatty Acid Elongase 1 (ELOVL1))

Alternative Name: ELOVL1 (ELOVL1 Products)

Synonyms: AA407424 antibody, BB151133 antibody, Ssc1 antibody, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 antibody, ELOVL fatty acid elongase 1 antibody, Elovl1 antibody, ELOVL1 antibody

Background:

Background: Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.

Aliases: 3 keto acyl CoA synthase ELOVL1 antibody, 3-keto acyl-CoA synthase ELOVL1 antibody, CGI 88 antibody, Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 1 antibody, Elongation of very long chain fatty acids like 1 antibody, Elongation of very long chain fatty acids protein 1 antibody, ELOV1_HUMAN antibody, ELOVL 1 antibody, ELOVL FA elongase 1 antibody, ELOVL fatty acid elongase 1 antibody, ELOVL1 antibody, Ssc1 antibody, Ssc1, mouse, homolog of antibody, very long chain 3 oxoacyl CoA synthase 1 antibody, Very-long-chain 3-oxoacyl-CoA synthase 1 antibody

UniProt: Q9BW60