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EHD3 antibody (AA 269-498)

EHD3 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7151461
  • Target See all EHD3 Antibodies
    EHD3 (EH-Domain Containing 3 (EHD3))
    Binding Specificity
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 269-498
    Reactivity
    • 25
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 22
    • 3
    Rabbit
    Clonality
    • 23
    • 2
    Polyclonal
    Conjugate
    • 13
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EHD3 antibody is un-conjugated
    Application
    • 15
    • 11
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human EH domain-containing protein 3 protein (269-498AA)
    Isotype
    IgG
    Top Product
    Discover our top product EHD3 Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    EHD3 (EH-Domain Containing 3 (EHD3))
    Alternative Name
    EHD3 (EHD3 Products)
    Synonyms
    PAST3 antibody, Ehd2 antibody, EHD3 antibody, si:ch211-147c1.2 antibody, MGC146452 antibody, EH domain containing 3 antibody, EH-domain containing 3 antibody, EH domain containing 3 L homeolog antibody, EHD3 antibody, Ehd3 antibody, ehd3 antibody, ehd3.L antibody
    Background

    Background: ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (PubMed:25686250). In vitro causes tubulation of endocytic membranes (PubMed:24019528). Binding to phosphatidic acid induces its membrane tubulation activity (By similarity). Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology (PubMed:16251358, PubMed:17233914, PubMed:19139087, PubMed:23781025). Involved in the recycling of internalized D1 dopamine receptor (PubMed:21791287). Plays a role in cardiac protein trafficking probably implicating ANK2 (PubMed:20489164). Involved in the ventricular membrane targeting of SLC8A1 and CACNA1C and probably the atrial membrane localization of CACNA1GG and CACNA1H implicated in the regulation of atrial myocyte exitability and cardiac conduction (By similarity). In conjunction with EHD4 may be involved in endocytic trafficking of KDR/VEGFR2 implicated in control of glomerular function (By similarity). Involved in the rapid recycling of integrin beta-3 implicated in cell adhesion maintenance (PubMed:23781025). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing (By similarity). Plays a role in the formation of the ciliary vesicle, an early step in cilium biogenesis, possibly sharing redundant functions with EHD1 (PubMed:25686250).

    Aliases: EHD3 antibody, EHD2 antibody, PAST3EH domain-containing protein 3 antibody, PAST homolog 3 antibody

    UniProt
    Q9NZN3
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