UBR1 antibody (AA 722-862)
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- Target See all UBR1 Antibodies
- UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))
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Binding Specificity
- AA 722-862
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UBR1 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human E3 ubiquitin-protein ligase UBR1 protein (722-862AA)
- Isotype
- IgG
- Top Product
- Discover our top product UBR1 Primary Antibody
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- Application Notes
- Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))
- Alternative Name
- UBR1 (UBR1 Products)
- Synonyms
- Dmel\\CG9086 antibody, Ubr1 antibody, UBR1 antibody, JBS antibody, AI504731 antibody, RGD1562326 antibody, Ubr1 ubiquitin ligase antibody, ubiquitin protein ligase E3 component n-recognin 1 antibody, E3 ubiquitin-protein ligase ubr-1 antibody, Ubr1 antibody, ubr1 antibody, UBR1 antibody, ubr-1 antibody
- Background
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Background: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
Aliases: E3 ubiquitin-protein ligase UBR1 antibody, JBS antibody, N-recognin-1 antibody, ubiquitin protein ligase E3 component n-recognin 1 antibody, Ubiquitin-protein ligase E3-alpha-1 antibody, Ubiquitin-protein ligase E3-alpha-I antibody, UBR1 antibody, UBR1_HUMAN antibody
- UniProt
- Q8IWV7
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