TRIM37 antibody (AA 301-600)

Catalog No. ABIN7151266

Product Details anti-TRIM37 Antibody

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Binding Specificity: AA 301-600

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM37 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase TRIM37 protein (301-600AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TRIM37

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Alternative Name: TRIM37 (TRIM37 Products)

Background:

Background: E3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:23769972). Mediates monoubiquitination of \\\'Lys-119\\\' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:25470042). Has anti-HIV activity (PubMed:24317724).

Aliases: E3 ubiquitin protein ligase TRIM37 antibody, E3 ubiquitin-protein ligase TRIM37 antibody, KIAA0898 antibody, MUL antibody, MUL protein antibody, Mulibrey nanism gene antibody, Mulibrey nanism protein antibody, POB 1 antibody, POB1 antibody, RING B box coiled coil protein antibody, TEF 3 antibody, TEF3 antibody, TRI37_HUMAN antibody, TRIM 37 antibody, Trim37 antibody, Tripartite motif containing 37 antibody, Tripartite motif containing 37 protein antibody, Tripartite motif containing protein 37 antibody, Tripartite motif-containing protein 37 antibody

UniProt: O94972