SH3RF1 antibody (AA 628-742) (HRP)

Catalog No. ABIN7151212

Product Details anti-SH3RF1 Antibody (HRP)

Target: SH3RF1 (SH3 Domain Containing Ring Finger 1 (SH3RF1))

Binding Specificity: AA 628-742

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3RF1 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase SH3RF1 protein (628-742AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SH3RF1

Target: SH3RF1 (SH3 Domain Containing Ring Finger 1 (SH3RF1))

Alternative Name: SH3RF1 (SH3RF1 Products)

Synonyms: SH3MD2 antibody, posh antibody, xPOSH antibody, rnf142 antibody, sh3md2 antibody, MGC135632 antibody, MGC189605 antibody, POSH antibody, RNF142 antibody, 2200003J05Rik antibody, Posh antibody, R75531 antibody, Sh3md2 antibody, si:ch211-114c9.2 antibody, si:dkey-15j16.4 antibody, wu:fi42f11 antibody, SH3 domain containing ring finger 1 antibody, SH3 domain containing ring finger 1 S homeolog antibody, SH3RF1 antibody, sh3rf1 antibody, sh3rf1.S antibody, Sh3rf1 antibody

Background:

Background: Acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9) (By similarity). May be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane.

Aliases: SH3RF1 antibody, KIAA1494 antibody, POSH antibody, POSH1 antibody, RNF142 antibody, SH3MD2 antibody, E3 ubiquitin-protein ligase SH3RF1 antibody, EC 2.3.2.27 antibody, Plenty of SH3s antibody, Protein POSH antibody, RING finger protein 142 antibody, RING-type E3 ubiquitin transferase SH3RF1 antibody, SH3 domain-containing RING finger protein 1 antibody, SH3 multiple domains protein 2 antibody

UniProt: Q7Z6J0