RNF6 antibody (AA 1-298)
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- Target See all RNF6 Antibodies
- RNF6 (RING Finger Protein 6 (RNF6))
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Binding Specificity
- AA 1-298
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RNF6 antibody is un-conjugated
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Application
- ELISA, Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human E3 ubiquitin-protein ligase RNF6 protein (1-298AA)
- Isotype
- IgG
- Top Product
- Discover our top product RNF6 Primary Antibody
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- Application Notes
- Recommended dilution: IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- RNF6 (RING Finger Protein 6 (RNF6))
- Alternative Name
- RNF6 (RNF6 Products)
- Synonyms
- 1200013I08Rik antibody, 5730419H05Rik antibody, AA537053 antibody, ring finger protein 6 antibody, ring finger protein (C3H2C3 type) 6 antibody, RNF6 antibody, Rnf6 antibody
- Background
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Background: E3 ubiquitin-protein ligase mediating \'Lys-48\'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates \'Lys-6\' and \'Lys-27\'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.
Aliases: E3 ubiquitin-protein ligase RNF6 antibody, Ring finger protein (C3H2C3 type) 6 antibody, Ring finger protein 6 antibody, RING H2 protein antibody, RING H2 protein RNF6 antibody, RNF 6 antibody, RNF6 antibody, RNF6_HUMAN antibody, SPG2 antibody
- UniProt
- Q9Y252
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size
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