RNF213 antibody (AA 202-350) (Biotin)

Catalog No. ABIN7151177

Product Details anti-RNF213 Antibody (Biotin)

Target: RNF213 (Ring Finger Protein 213 (RNF213))

Binding Specificity: AA 202-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF213 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase RNF213 protein (202-350AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RNF213

Target: RNF213 (Ring Finger Protein 213 (RNF213))

Alternative Name: RNF213 (RNF213 Products)

Background:

Background: E3 ubiquitin-protein ligase involved in angiogenesis (PubMed:21799892, PubMed:26278786, PubMed:26766444, PubMed:26126547). Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression (PubMed:26766444). Also has ATPase activity (PubMed:24658080, PubMed:26126547).

Aliases: ALK lymphoma oligomerization partner on chromosome 17 antibody, C17orf27 antibody, Chromosome 17 open reading frame 27 antibody, E3 ubiquitin-protein ligase RNF213 antibody, FLJ13051 antibody, KIAA1554 antibody, MGC46622 antibody, MGC9929 antibody, MYMY2 antibody, Mysterin antibody, MYSTR antibody, NET57 antibody, RING finger protein 213 antibody, RN213_HUMAN antibody, RNF 213 antibody, RNF213 antibody

UniProt: Q63HN8