PDZRN3 antibody (AA 133-404)

Catalog No. ABIN7151097

Product Details anti-PDZRN3 Antibody

Target: PDZRN3 (PDZ Domain Containing Ring Finger 3 (PDZRN3))

Binding Specificity: AA 133-404

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDZRN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase PDZRN3 protein (133-404AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PDZRN3

Target: PDZRN3 (PDZ Domain Containing Ring Finger 3 (PDZRN3))

Alternative Name: PDZRN3 (PDZRN3 Products)

Synonyms: MGC80196 antibody, pdzrn3 antibody, LNX3 antibody, SEMACAP3 antibody, 1110020C07Rik antibody, AI429718 antibody, AL023082 antibody, Semcap3 antibody, PDZ domain containing ring finger 3 antibody, PDZ domain containing ring finger 3 L homeolog antibody, PDZ domain containing RING finger 3b antibody, E3 ubiquitin-protein ligase PDZRN3 antibody, PDZ domain containing RING finger 3 antibody, PDZRN3 antibody, pdzrn3.L antibody, pdzrn3b antibody, LOC100228989 antibody, pdzrn3 antibody, Pdzrn3 antibody

Background:

Background: E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation (By similarity).

Aliases: E3 ubiquitin-protein ligase PDZRN3 antibody, KIAA1095 antibody, Ligand of Numb protein X 3 antibody, likely ortholog of mouse semaF cytoplasmic domain associated protein 3 antibody, LNX3 antibody, PDZ domain containing ring finger 3 antibody, PDZ domain-containing RING finger protein 3 antibody, Pdzrn3 antibody, Protein SEMACAP3 antibody, PZRN3_HUMAN antibody, SEMACAP3 antibody, Semaphorin cytoplasmic domain associated protein antibody, Semaphorin cytoplasmic domain-associated protein 3 antibody, SEMCAP3 antibody

UniProt: Q9UPQ7

Pathways: Skeletal Muscle Fiber Development