HECW2 antibody (AA 495-641)

Catalog No. ABIN7151037

Product Details anti-HECW2 Antibody

Target: HECW2 (HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 2 (HECW2))

Binding Specificity: AA 495-641

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HECW2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase HECW2 protein (495-641AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HECW2

Target: HECW2 (HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 2 (HECW2))

Alternative Name: HECW2 (HECW2 Products)

Synonyms: HECW2 antibody, NEDL2 antibody, A730039N16Rik antibody, D030049F17Rik antibody, Gm971 antibody, Nedl2 antibody, mKIAA1301 antibody, HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 antibody, E3 ubiquitin-protein ligase HECW2 antibody, HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2b antibody, Hecw2 antibody, HECW2 antibody, LOC531691 antibody, hecw2b antibody, hecw2 antibody

Background:

Background: E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73 (PubMed:12890487). Involved in the regulation of mitotic metaphase/anaphase transition (PubMed:24163370).

Aliases: C2 and WW domain-containing protein 2 antibody, E3 ubiquitin protein ligase HECW2 antibody, E3 ubiquitin-protein ligase HECW2 antibody, HECT antibody, HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 antibody, Hecw2 antibody, HECW2_HUMAN antibody, KIAA130 antibody, KIAA1301 antibody, NEDD4 like E3 ubiquitin protein ligase 2 antibody, NEDD4 Related E3 Ubiquitin Ligase antibody, NEDD4-like E3 ubiquitin-protein ligase 2 antibody

UniProt: Q9P2P5