FANCL antibody (AA 138-248)

Catalog No. ABIN7151021

Product Details anti-FANCL Antibody

Target: FANCL (Fanconi Anemia, Complementation Group L (FANCL))

Binding Specificity: AA 138-248

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCL antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase FANCL protein (138-248AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FANCL

Target: FANCL (Fanconi Anemia, Complementation Group L (FANCL))

Alternative Name: FANCL (FANCL Products)

Synonyms: FAAP43 antibody, PHF9 antibody, POG antibody, 2010322C19Rik antibody, AW554273 antibody, B230118H11Rik antibody, Phf9 antibody, Pog antibody, gcd antibody, Fanconi anemia complementation group L antibody, Fanconi anemia, complementation group L antibody, FANCL antibody, Fancl antibody

Background:

Background: Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth.

Aliases: E3 ubiquitin-protein ligase FANCL antibody, FAAP43 antibody, Fancl antibody, FANCL_HUMAN antibody, Fanconi anemia complementation group L antibody, Fanconi anemia group L protein antibody, Fanconi anemia-associated polypeptide of 43 kDa antibody, FLJ10335 antibody, PHD finger protein 9 antibody, PHF9 antibody, POG antibody, Ubiquitin ligase protein FANCL antibody

UniProt: Q9NW38

Pathways: DNA Damage Repair