RANBP2 antibody (AA 2601-2802)

Catalog No. ABIN7150974

Product Details anti-RANBP2 Antibody

Target: RANBP2 (RAN Binding Protein 2 (RANBP2))

Binding Specificity: AA 2601-2802

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RANBP2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 SUMO-protein ligase RanBP2 protein (2601-2802AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RANBP2

Target: RANBP2 (RAN Binding Protein 2 (RANBP2))

Alternative Name: RANBP2 (RANBP2 Products)

Background:

Background: E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Binds single-stranded RNA (in vitro). May bind DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at \'Lys-490\' which is essential for the proper assembly of PML-NB.

Aliases: 358 kDa nucleoporin antibody, ANE1 antibody, E3 SUMO-protein ligase RanBP2 antibody, IIAE3 antibody, Nuclear pore complex protein Nup358 antibody, Nucleoporin 358 antibody, Nucleoporin Nup358 antibody, NUP358 antibody, p270 antibody, RAN binding protein 2 antibody, Ran-binding protein 2 antibody, RANBP2 antibody, RBP2_HUMAN antibody, Transformation related protein 2 antibody, TRP 1 antibody, TRP 2 antibody, TRP1 antibody, TRP2 antibody

UniProt: P49792

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus