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DTNBP1 antibody (AA 258-351) (HRP)

DTNBP1 Reactivity: Human ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN7150913
  • Target See all DTNBP1 Antibodies
    DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
    Binding Specificity
    • 15
    • 9
    • 8
    • 7
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 258-351
    Reactivity
    • 58
    • 28
    • 27
    • 15
    • 1
    • 1
    Human
    Host
    • 88
    • 2
    Rabbit
    Clonality
    • 88
    • 2
    Polyclonal
    Conjugate
    • 27
    • 9
    • 9
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DTNBP1 antibody is conjugated to HRP
    Application
    • 47
    • 42
    • 30
    • 26
    • 26
    • 11
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Dysbindin protein (258-351AA)
    Isotype
    IgG
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    Discover our top product DTNBP1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
    Alternative Name
    DTNBP1 (DTNBP1 Products)
    Synonyms
    5430437B18Rik antibody, AW048963 antibody, Bloc1s8 antibody, dysbindin antibody, sdy antibody, BLOC1S8 antibody, DBND antibody, HPS7 antibody, My031 antibody, SDY antibody, dtnbp1 antibody, zgc:56462 antibody, MGC83903 antibody, dbnd antibody, hps7 antibody, my031 antibody, MGC85477 antibody, DTNBP1 antibody, CG6856 antibody, Ddysb antibody, Dmel\\CG6856 antibody, si:ch211-285p6.1 antibody, dystrobrevin binding protein 1 antibody, Dysbindin antibody, dystrobrevin binding protein 1a antibody, dystrobrevin binding protein 1 L homeolog antibody, dystrobrevin binding protein 1 S homeolog antibody, dystrobrevin binding protein 1b antibody, Dtnbp1 antibody, DTNBP1 antibody, dtbp1 antibody, dtnbp1a antibody, dtnbp1.L antibody, dtnbp1.S antibody, dtnbp1 antibody, Dysb antibody, dtnbp1b antibody
    Background

    Background: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway.

    Aliases: DTBP1_HUMAN antibody, DTNBP1 antibody, Dysbindin antibody, Dysbindin-1 antibody, Dystrobrevin binding protein 1 antibody, Dystrobrevin-binding protein 1 antibody, Hermansky Pudlak syndrome 7 protein antibody, Hermansky-Pudlak syndrome 7 protein antibody, HPS7 antibody, HPS7 protein antibody

    UniProt
    Q96EV8
    Pathways
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling
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