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DSCAM antibody (AA 1711-1867) (Biotin)

DSCAM Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7150650
  • Target See all DSCAM Antibodies
    DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))
    Binding Specificity
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1711-1867
    Reactivity
    • 19
    • 18
    • 11
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 22
    • 6
    • 1
    Rabbit
    Clonality
    • 24
    • 5
    Polyclonal
    Conjugate
    • 12
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DSCAM antibody is conjugated to Biotin
    Application
    • 13
    • 13
    • 10
    • 10
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Down syndrome cell adhesion molecule protein (1711-1867AA)
    Isotype
    IgG
    Top Product
    Discover our top product DSCAM Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))
    Alternative Name
    DSCAM (DSCAM Products)
    Synonyms
    CHD2-42 antibody, CHD2-52 antibody, Dscam antibody, DSCAM antibody, chd2-42 antibody, chd2-52 antibody, dscam antibody, GB15141 antibody, 4932410A21Rik antibody, 43Bc antibody, CG17800 antibody, CT39257 antibody, DScam antibody, DmDscam antibody, Dm_2R:13612 antibody, Dmel\\CG17800 antibody, Dscam-hv antibody, Dscam1 antibody, FBgn0033159 antibody, Neu1 antibody, dScam antibody, l(2)05518 antibody, l(2)43Bc antibody, p270 antibody, DS cell adhesion molecule antibody, Down syndrome cell adhesion molecule antibody, Down syndrome cell adhesion molecule a antibody, Down syndrome cell adhesion molecule 1 antibody, Down syndrome cell adhesion molecule-like protein Dscam2 antibody, down syndrome cell adhesion molecule antibody, Down syndrome cell adhesion molecule L homeolog antibody, DSCAM antibody, Dscam antibody, dscam antibody, dscama antibody, Dscam1 antibody, LOC5573626 antibody, CpipJ_CPIJ006173 antibody, dscam.L antibody
    Background

    Background: Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies (PubMed:10925149). Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC. In spinal chord development plays a role in guiding commissural axons projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding (PubMed:18585357, PubMed:19196994). Enhances netrin-induced phosphorylation of PAK1 and FYN (PubMed:15169762). Mediates intracellular signaling by stimulating the activation of MAPK8 and MAP kinase p38 (PubMed:18585357, PubMed:19196994). Adhesion molecule that promotes lamina-specific synaptic connections in the retina: expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions (By similarity).

    Aliases: CHD2 42 antibody, CHD2 52 antibody, CHD2 antibody, Down syndrome cell adhesion molecule antibody, DSCAM antibody, DSCAM_HUMAN antibody, human CHD2-52 down syndrome cell adhesion molecule 2, 9 antibody, OTTHUMP00000109193 2 antibody, SD11109p antibody

    UniProt
    O60469
    Pathways
    Regulation of Cell Size
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