CRCP antibody (AA 1-115)

Catalog No. ABIN7150470

Product Details anti-CRCP Antibody

Target: CRCP (CGRP Receptor Component (CRCP))

Binding Specificity: AA 1-115

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRCP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human DNA-directed RNA polymerase III subunit RPC9 protein (1-115AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CRCP

Target: CRCP (CGRP Receptor Component (CRCP))

Alternative Name: CRCP (CRCP Products)

Synonyms: rcp9 antibody, LOC692930 antibody, zgc:153737 antibody, Rcp9 antibody, AL022669 antibody, CGRP-RCP antibody, CGRPRCP antibody, RCP antibody, RCP9 antibody, Cgrp-rcp antibody, CGRP receptor component antibody, calcitonin gene-related peptide-receptor component protein antibody, crcp antibody, LOC692930 antibody, Rcp9 antibody, CRCP antibody, Crcp antibody

Background:

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).

Aliases: Calcitonin gene related peptide receptor component antibody, Calcitonin gene related peptide receptor component protein antibody, Calcitonin gene-related peptide-receptor component protein antibody, CGRP receptor component protein antibody, CGRP-RCP antibody, CGRP-receptor component protein antibody, CGRPRCP antibody, CRCP antibody, DNA-directed RNA polymerase III subunit RPC9 antibody, HsC17 antibody, RCP antibody, RCP9 antibody, RNA polymerase III subunit C9 antibody, RPC9_HUMAN antibody

UniProt: O75575