POLR3F antibody (AA 1-270) (HRP)
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- Target See all POLR3F Antibodies
- POLR3F (Polymerase (RNA) III (DNA Directed) Polypeptide F, 39 KDa (POLR3F))
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Binding Specificity
- AA 1-270
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This POLR3F antibody is conjugated to HRP
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human DNA-directed RNA polymerase III subunit RPC6 protein (1-270AA)
- Isotype
- IgG
- Top Product
- Discover our top product POLR3F Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- POLR3F (Polymerase (RNA) III (DNA Directed) Polypeptide F, 39 KDa (POLR3F))
- Alternative Name
- POLR3F (POLR3F Products)
- Synonyms
- 2810411G20Rik antibody, 3010019O03Rik antibody, 3110032A07Rik antibody, RPC39 antibody, RPC6 antibody, zgc:56299 antibody, zgc:76983 antibody, RNA polymerase III subunit F antibody, polymerase (RNA) III (DNA directed) polypeptide F antibody, POLR3F antibody, Polr3f antibody, polr3f antibody
- Background
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Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
Aliases: DNA directed RNA polymerase III 39 kDa polypeptide antibody, DNA directed RNA polymerase III 39 kDa polypeptide F antibody, DNA directed RNA polymerase III subunit F antibody, DNA directed RNA polymerase III subunit RPC6 antibody, DNA directed RNA polymerases III 39 kDa polypeptide antibody, DNA-directed RNA polymerase III subunit F antibody, DNA-directed RNA polymerase III subunit RPC6 antibody, MGC13517 antibody, Polr3f antibody, Polymerase (RNA) III (DNA directed) polypeptide F antibody, RNA polymerase III 39 kDa subunit antibody, RNA polymerase III C39 subunit antibody, RNA polymerase III subunit C6 antibody, RPC 39 antibody, RPC 6 antibody, RPC39 antibody, RPC6 antibody, RPC6_HUMAN antibody
- UniProt
- Q9H1D9
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