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POLR3E antibody (AA 1-260)

POLR3E Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7150462
  • Target See all POLR3E Antibodies
    POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))
    Binding Specificity
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-260
    Reactivity
    • 23
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 21
    • 2
    Rabbit
    Clonality
    • 21
    • 2
    Polyclonal
    Conjugate
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLR3E antibody is un-conjugated
    Application
    • 9
    • 9
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human DNA-directed RNA polymerase III subunit RPC5 protein (1-260AA)
    Isotype
    IgG
    Top Product
    Discover our top product POLR3E Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))
    Alternative Name
    POLR3E (POLR3E Products)
    Synonyms
    RPC5 antibody, SIN antibody, Sin antibody, MGC78924 antibody, RGD1308086 antibody, wu:fb12d10 antibody, wu:fs42e03 antibody, zgc:55592 antibody, RNA polymerase III subunit E antibody, polymerase (RNA) III (DNA directed) polypeptide E antibody, polymerase (RNA) III (DNA directed) polypeptide E (80kD) L homeolog antibody, polymerase (RNA) III (DNA directed) polypeptide E (80kD) antibody, DNA-directed RNA polymerase III subunit RPC5 antibody, POLR3E antibody, Polr3e antibody, polr3e.L antibody, polr3e antibody, LOC608689 antibody
    Background

    Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).

    Aliases: POLR3E antibody, KIAA1452 antibody, DNA-directed RNA polymerase III subunit RPC5 antibody, RNA polymerase III subunit C5 antibody, DNA-directed RNA polymerase III 80 kDa polypeptide antibody

    UniProt
    Q9NVU0
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