MCM6 antibody (AA 562-821)

Catalog No. ABIN7150339

Product Details anti-MCM6 Antibody

Target: MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

Binding Specificity: AA 562-821

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human DNA replication licensing factor MCM6 protein (562-821AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MCM6

Target: MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

Alternative Name: MCM6 (MCM6 Products)

Background:

Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for \\\'once per cell cycle\\\' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.

Aliases: DNA replication licensing factor MCM6 antibody, MCG40308 antibody, Mcm6 antibody, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) antibody, MCM6 minichromosome maintenance deficient 6 antibody, MCM6_HUMAN antibody, Minichromosome maintenance complex component 6 antibody, Minichromosome maintenance deficient (mis5 S. pombe) 6 antibody, Minichromosome maintenance deficient 6 homolog antibody, Minichromosome maintenance protein 6 antibody, Mis5 antibody, MIS5 homolog antibody, p105MCM antibody

UniProt: Q14566

Pathways: DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA