POLH antibody (AA 408-609) (HRP)
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- Target See all POLH Antibodies
- POLH (Polymerase (DNA Directed), eta (POLH))
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Binding Specificity
- AA 408-609
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This POLH antibody is conjugated to HRP
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human DNA polymerase eta protein (408-609AA)
- Isotype
- IgG
- Top Product
- Discover our top product POLH Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- POLH (Polymerase (DNA Directed), eta (POLH))
- Alternative Name
- POLH (POLH Products)
- Synonyms
- POLH antibody, fc50a12 antibody, wu:fc50a12 antibody, zgc:136881 antibody, zgc:152642 antibody, RAD30 antibody, RAD30A antibody, XP-V antibody, XPV antibody, polymerase (DNA directed), eta S homeolog antibody, DNA polymerase eta antibody, polymerase (DNA directed), eta antibody, putative DNA polymerase eta antibody, polymerase (DNA directed), eta (RAD 30 related) antibody, polh.S antibody, POLH antibody, polh antibody, Tb10.70.6190 antibody, LINJ_21_0690 antibody, Polh antibody, LOC100443019 antibody
- Background
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Background: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5\'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.
Aliases: DNA polymerase eta antibody, FLJ16395 antibody, FLJ21978 antibody, Polh antibody, POLH_HUMAN antibody, polymerase DNA directed eta antibody, RAD30 antibody, RAD30 homolog A antibody, RAD30A antibody, Xeroderma pigmentosum variant type protein antibody, XP V antibody, XPV antibody
- UniProt
- Q9Y253
- Pathways
- DNA Damage Repair
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