ALKBH2 antibody (AA 1-261)

Catalog No. ABIN7150217

Product Details anti-ALKBH2 Antibody

Target: ALKBH2 (AlkB, Alkylation Repair Homolog 2 (ALKBH2))

Binding Specificity: AA 1-261

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALKBH2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human DNA oxidative demethylase ALKBH2 protein (1-261AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ALKBH2

Target: ALKBH2 (AlkB, Alkylation Repair Homolog 2 (ALKBH2))

Alternative Name: ALKBH2 (ALKBH2 Products)

Synonyms: si:dkey-65b12.2 antibody, ABH2 antibody, 9530023G02 antibody, AU016977 antibody, Abh2 antibody, mABH2 antibody, RGD1306377 antibody, alkB homolog 2, alpha-ketoglutarate dependent dioxygenase antibody, alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase antibody, ALKBH2 antibody, alkbh2 antibody, Alkbh2 antibody

Background:

Background: Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.

Aliases: 2OG Fe(II) oxy DC1 antibody, 9530023G02 antibody, ABH 2 antibody, ABH2 antibody, alkB alkylation repair homolog 2 antibody, ALKB2_HUMAN antibody, ALKBH2 alkB antibody, ALKBH2 antibody, Alkylated DNA repair protein alkB homolog antibody, Alkylated DNA repair protein alkB homolog 2 antibody, Alkylation repair homolog 2 antibody, Alpha ketoglutarate dependent dioxygenase alkB homolog 2 antibody, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 antibody, AU016977 antibody, DNA oxidative demethylase ALKBH2 antibody, EC 1.14.11. antibody, FLJ99103 antibody, hABH2 antibody, mABH2 antibody, MGC90512 antibody, Oxy DC1 antibody

UniProt: Q6NS38

Pathways: DNA Damage Repair